Methadone
Methadone
CAS Number:
1095–90-5
Batch Molecular Formula:
C21H27NO
Batch Molecular Weight:
309.445 g/mol
Physical Appearance:
White Crystalline Solid / Powder
Solubility:
Very Soluble in Water
Storage:
Store at RT
Methadone is a long-acting synthetic opioid primarily used for pain management and opioid use disorder (OUD) treatment. It is a controlled substance due to its potential for abuse and dependence. When used appropriately under medical supervision, methadone is a highly effective medication.
Types of Methadone
1. Medical Formulations
Tablets: Available in different strengths (e.g., 5 mg, 10 mg).
Oral Solutions: Commonly used in OUD treatment (e.g., Methadose).
Injectable Form: Used in hospital settings for severe pain or detoxification.
2. Immediate-Release Methadone
Provides quick relief for severe pain.
Used in acute medical settings.
3. Long-Acting Methadone
Used in maintenance therapy for opioid addiction.
Administered once daily due to its long half-life.
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Effects
1. Therapeutic Effects
Relieves pain by acting on opioid receptors in the CNS.
Suppresses opioid withdrawal symptoms and cravings.
Stabilizes individuals with OUD, allowing for normal functioning.
2. Side Effects
Common:
Drowsiness, dry mouth, and sweating.
Nausea, vomiting, and constipation.
Serious:
Respiratory depression (potentially life-threatening).
QT prolongation (risk of arrhythmias).
Physical dependence with long-term use.
Usage
1. Medical Use
Opioid Use Disorder (OUD):
Maintenance therapy to prevent withdrawal symptoms and reduce cravings.
Reduces the risk of overdose and transmission of infectious diseases (e.g., HIV, hepatitis) by discouraging illicit opioid use.
Chronic Pain Management:
Prescribed for severe pain unresponsive to other medications, especially in cancer or palliative care.
2. Non-Medical Use
Occasionally misused for its sedative and euphoric effects.
Disclaimer
Products falling in to controlled substance category / list of schedule drugs shall be exported directly from the manufacturer principals only against receipt of original import permission issued by concerned authorities of the importing country. Products protected by valid patents are not offered for sale in countries where the sale of such products constitutes a patent infringement and its liability is at buyer’s risk. Most OTC drugs are not reviewed and approved by FDA, however, they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies. This is only for study not for any Human / Veterinary use. (Condition Apply)* Delphis Pharmaceutical India warns the buyers / importers not to use/sell/procure any goods to achieve a product which might be knowingly causing an infringement / controlled / banned drugs. Delphis Pharmaceutical India is not responsible or liable for the same.
